Most neurodegenerative diseases are currently incurable, with large social and economic impacts.Recently, there has been renewed interest in investigating natural products in the modern drug discovery paradigm as novel, bioactive small molecules.Moreover, the discovery of potential therapies for neurological disorders is challenging and involves de
Abstract High-dose melphalan at 200 mg/m2 (MEL-200) is the standard conditioning regimen before autologous stem cell transplantation (ASCT) in patients with multiple myeloma (MM).Busulfan (BU) and cyclophosphamide (CY) can be used as alternatives when MEL is unavailable.However, most studies on BU/CY conditioning regimens were conducted before prot
Abstract Background The objective of the present study aimed to investigate the effect of CoQ10 treatment on isoprenaline (ISO)-induced cardiac remodeling in rats.Methods Rats were divided into three groups namely Control group, ISO treated group and CoQ10 + ISO treated group, each consisting of 6 rats.The cardiac specific CK-MB, AST, ALT activity